Heparin sodium CAS 9041-08-1

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale:Heparin lithium

Lebitso le leng:Heparin sodium letsoai

Nomoro ea CAS:9041-08-1

Kereiti:E hlabang (//) /crude

Tlhaloso:EP/USP/BP/CP/IP

Lintho tsa Lik'hemik'hale:Heparin sodium ke phofo e tšoeu kapa e bosoeu, ha e na monko, hygroscopic, e qhibiliha ka metsing, ha e qhibilihe ka har'a metsoako ea tlhaho e kang ethanol le acetone.E na le tefiso e matla e mpe ka tharollo ea metsi 'me e ka kopana le li-cations tse ling ho theha limolek'hule tsa limolek'hule.Litharollo tsa metsi li tsitsitse haholoanyane ho pH 7. E na le mefuta e mengata ea tšebeliso ea meriana.E sebelisoa ho phekola infarction e matla ea myocardial le lefu la sebete la pathogenic.E ka sebelisoa hammoho le ribonucleic acid ho eketsa katleho ea lefu la sebete la B. Ha e kopantsoe le chemotherapy, ho molemo ho thibela thrombosis.E ka fokotsa lipids ea mali le ho ntlafatsa ts'ebetso ea 'mele ea ho itšireletsa mafung.e boetse e na le karolo.

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Kopo

Heparin sodium ke setlhare sa anticoagulant, e leng ntho ea mucopolysaccharide.Ke letsoai la sodium la glucosamine sulfate le ntšitsoeng ho mucosa ea mala ea likolobe, likhomo le linku.bohareng.Heparin sodium e na le mesebetsi ea ho thibela ho bokellana ha liplatelete le timetso, ho thibela phetoho ea fibrinogen ho fibrin monomer, ho thibela sebopeho sa thromboplastin le ho hanela thromboplastin e entsoeng, ho thibela phetoho ea prothrombin ho thrombin le antithrombin.

Heparin sodium e ka lieha kapa ea thibela tšollo ea mali ka in vitro le in vivo.Mokhoa oa eona oa ts'ebetso o rarahane haholo mme o ama likhokahano tse ngata ts'ebetsong ea coagulation.Mesebetsi ea eona ke: ① Thibela sebopeho le ts'ebetso ea thromboplastin, kahoo e thibela prothrombin ho fetoha thrombin;②Libakeng tse phahameng, e ka thibela thrombin le lintlha tse ling tsa coagulation, e thibelang fibrinogen ho fetoha protheine ea fibrin;③ e ka thibela ho bokellana le ho senngoa ha liplatelete.Ho phaella moo, phello ea anticoagulant ea sodium heparin e ntse e amana le sulfate e matla ea sulfate ka molek'hule ea eona.Lintho tsa alkaline tse qosoang hantle joalo ka protamine kapa toluidine blue li ka fokotsa tefiso ea eona e mpe, kahoo e ka thibela anticoagulant ea eona.coagulation.Hobane heparin e ka kenya tšebetsong le ho lokolla lipoprotein lipase 'meleng, hydrolyze triglyceride le low-density lipoprotein ho chylomicrons, ka hona e na le phello ea hypolipidemic.

Heparin sodium e ka sebelisoa ho phekola lefu le matla la thromboembolic, disseminated intravascular coagulation (DIC).Lilemong tsa morao tjena, ho fumanoe hore heparin e na le phello ea ho tlosa lipids tsa mali.Ente e kenang ka methapo kapa ente e tebileng ea mesifa (kapa ente e ka tlas'a letlalo), li-unit tse 5,000 ho isa ho tse 10,000 nako le nako.Heparin sodium ha e na chefo e nyane mme tšekamelo ea ho tsoa mali ka tšohanyetso ke kotsi ea bohlokoa ka ho fetesisa ea heparin.E sa sebetse ka molomo, e tlameha ho tsamaisoa ka ente.Ente ea intramuscular kapa subcutaneous injection e halefisa haholo, ka linako tse ling ho ka 'na ha e-ba le maikutlo a ho kula,' me ho feta tekano ho ka ba ha baka ho tšoaroa ke pelo;ka linako tse ling ho lahleheloa ke moriri le lets'ollo.Ho phaella moo, e ntse e ka baka ho robeha ho sa tloaelehang.Tšebeliso ea nako e telele ka linako tse ling e ka baka thrombosis, e ka bang phello ea ho fokotseha ha anticoagulase-III.Sodium ea Heparin e hanyetsanoa ho bakuli ba nang le tšekamelo ea ho tsoa mali, sebete se matla le ho se sebetse hantle ha renal, khatello e matla ea mali, hemophilia, intracranial hemorrhage, peptic ulcer, basali ba bakhachane le postpartum, lihlahala tsa visceral, tsietsi le ho buuoa.